Here a couple of suggestions. I have put together for those who have a limited time in Rome and want to see as much they can on a guided tour!
Option 1
Vatican museums (Sixtine Chapel), St. Peter's basilica, Colosseum, Forum
Option 2
Trevi Fountain, Colonna Square, Pantheon| Ghetto, Teatro di Marcello, Capitol Square, Forum, Colosseum
We had a great tour with Cynthia she has a wealth of knowledge on Rome’s history and makes it come alive and personal. We had a awesome time at the Forum,Colosseum, St Peters and Vatican Museum. Trivi Fountain was very crowded but still a great time. Went back in the evening (via her suggestion) and it was beautiful in the lights! Our tour also had a time that we got to spend visiting with her because it began to pour down rain.She took us to a quaint restaurant where we spent some time chatting and eating. We really enjoyed our day in Rome!!!!!